Pigmented progressive purpuric dermatosis
https://en.wikipedia.org/wiki/Pigmented_purpuric_dermatosis
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Schamberg disease ― mwamuna wa zaka 26 amene ali ndi chigamba cha mtundu wopanda zizindikiro komanso telangiectasia pa mabere.
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References
Pigmented Purpuric Dermatoses: A Complete Narrative Review 34070260 NIH
Pigmented purpuric dermatoses (PPD) ndi gulu lazikhalidwe zapakhungu zodziwika ndi madera ango'ono'ono akukha magazi pansi pakhungu chifukwa cha capillaritis. PPD imayamba kukhala mawuli ofiira mpaka ofiirira omwe pambuyo pake amasanduka golden‑brown pamene hemosiderin imalowetsedwa.
Pigmented purpuric dermatoses (PPD) include several skin diseases characterized by multiple petechial hemorrhage as consequence of capillaritis. PPD generally present with red to purple macules that progressively evolve to golden-brown color as the hemosiderin is reabsorbed.
Schamberg Disease 32809367 NIH
Schamberg disease ndi mtundu wodziwika kwambiri wa pigmented purpuric dermatoses (PPDs), womwe ndi matenda osatha akhungu omwe amadziwika ndi purpuric eruptions, komanso kuchuluka kwa purpura (0.3–1 cm). Ma PPD amagawidwa m'mitundu isanu: Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot‑Blum purpura, eczematoid‑like purpura of Doucas and Kapetanakis. Schamberg disease (SD) amadziwikanso kuti progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressive, Schamberg's purpura. Imakhudza kwambiri amuna ndipo imawonekera pa lower extremities, komanso imatha kuchitika pa thighs, buttocks, trunk, kapena upper extremities.
Schamberg disease represents the most common type of pigmented purpuric dermatoses (PPDs), a chronic, benign, cutaneous eruptions characterized by petechiae, purpura, and increased skin pigmentation (brown, red, or yellow patchy). The PPDs are grouped into five clinical entities: Schamberg's purpura, Majocchi purpura, lichen aureus, Gougerot-Blum purpura and, eczematoid-like purpura of Doucas and Kapetanakis. Schamber disease (SD) has also been called: progressive pigmentary dermatosis of Schamberg, purpura pigmentosa progressive and, Schamberg's purpura. It is commonly seen in males and mainly affects the tibial regions, and could involve thighs, buttocks, trunk, or upper extremities.
Characteristics and Clinical Manifestations of Pigmented Purpuric Dermatosis 26273156 NIH
Zambiri za odwala 113 omwe ali ndi PPD adawunikidwa, kuphatikiza 38 omwe adachita kafukufuku wapakhungu pa kafukufukuyu. Mitundu yodziwika bwino yachipatala inali matenda a Schamberg (60.5%). Zinthu zina pambali pa PPD zinali kuthamanga kwa magazi (15.8%), shuga (10.5%), ndi ena. Mbiri yamankhwala idavumbulutsa ma statins (13.2%), beta blockers (10.5%), ndi ena. Zomwe zingatheke zokhudzana ndi PPD zikuphatikizapo matenda aposachedwapa apamwamba a kupuma (5.3%), kuyimirira kwa nthawi yaitali kumayambitsa mphamvu ya orthostatic (orthostatic pressure) (2.6%), ndi masewera olimbitsa thupi (2.6%). Chithandizo chinaperekedwa kwa odwala 36 (94.7%) – oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy.
Information on 113 patients with PPD was analyzed, and 38 subjects with skin biopsy were included for this study. Schamberg's disease was the most frequent clinical type (60.5%). Concomitant diseases included hypertension (15.8%), diabetes (10.5%), and others. Associated medication histories included statins (13.2%), beta blockers (10.5%), and others. Possibly associated etiologic factors were recent upper respiratory infection (5.3%), high orthostatic pressure due to prolonged standing (2.6%), and strenuous exercise (2.6%). A total of 36 patients (94.7%) were treated with one or more treatment methods, including oral antihistamines, pentoxifylline, topical steroids, and/or phototherapy.
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